Name: WDR24 rabbit pAb
SKU: WP6270
Price: 268 USD
Availability: InStock

WDR24 rabbit pAb

Ucallm_WP6270-50

Price range: $268.00 through $328.00

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SKU: WP6270-100

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Product details

Background:

Specifications

Size	50μL/100μL
Target	WDR24
Reactivity	Human, Mouse
Applications	WB
MW(Calculated)	87kD
MW(Observed)
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-2000
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	Synthesized peptide derived from human WDR24
Specificity	This antibody detects endogenous levels of WDR24 at Human, Mouse
Gene Name	WDR24 C16orf21 JFP7
Protein Name	WD repeat-containing protein 24
Other Name
Species	Human
Gene ID	84219
Uniprot	Q96S15,
Species.1	Mouse
Gene ID.1	268933
Uniprot.1	Q8CFJ9
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	Lysosome membrane .
Tissue Expression
Signaling_pathway	Environmental Information Processing >> Signal transduction >> mTOR signaling pathway
Research Areas
Function	As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway . Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex . It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 . In addition to its role in regulation of the TORC1 complex, promotes the acidification of lysosomes and facilitates autophagic flux .