Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human ZRAN1 AA range: 255-305
Specificity
This antibody detects endogenous levels of ZRAN1 at Human/Mouse
Gene Name
ZRANB1 TRABID
Protein Name
ZRAN1
Other Name
Species
Human
Gene ID
54764
Uniprot
Q9UGI0,
Species.1
Mouse
Gene ID.1
360216
Uniprot.1
Q7M760
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Cytoplasm . Nucleus . Enriched in punctate localization in the cytoplasm. .
Tissue Expression
Widely expressed.
Signaling_pathway
Research Areas
Function
Domain:The OTU domain mediates the deubiquitinating activity.,Domain:The RanBP2-type zinc fingers mediate the specific interaction with 'Lys-63'-linked ubiquitin.,Function:Positive regulator of the Wnt signaling pathway that specifically cleaves 'Lys-63'-linked ubiquitin chains. Acts by deubiquitinating APC protein, a negative regulator of Wnt-mediated transcription. May also modulate TNF-alpha signaling.,similarity:Belongs to the peptidase C64 family.,similarity:Contains 1 OTU domain.,similarity:Contains 3 RanBP2-type zinc fingers.,subunit:Interacts with APC and TRAF6.,tissue specificity:Widely expressed.,