SKU: WP16795 Categories: ,

ZRAN1 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP16795-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetZRAN1
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)78kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human ZRAN1 AA range: 255-305
SpecificityThis antibody detects endogenous levels of ZRAN1 at Human/Mouse
Gene NameZRANB1 TRABID
Protein NameZRAN1
Other Name
SpeciesHuman
Gene ID54764
UniprotQ9UGI0,
Species.1Mouse
Gene ID.1360216
Uniprot.1Q7M760
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCytoplasm . Nucleus . Enriched in punctate localization in the cytoplasm. .
Tissue ExpressionWidely expressed.
Signaling_pathway
Research Areas
FunctionDomain:The OTU domain mediates the deubiquitinating activity.,Domain:The RanBP2-type zinc fingers mediate the specific interaction with 'Lys-63'-linked ubiquitin.,Function:Positive regulator of the Wnt signaling pathway that specifically cleaves 'Lys-63'-linked ubiquitin chains. Acts by deubiquitinating APC protein, a negative regulator of Wnt-mediated transcription. May also modulate TNF-alpha signaling.,similarity:Belongs to the peptidase C64 family.,similarity:Contains 1 OTU domain.,similarity:Contains 3 RanBP2-type zinc fingers.,subunit:Interacts with APC and TRAF6.,tissue specificity:Widely expressed.,
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