Price range: $268.00 through $328.00
Background:
This gene encodes a member of the amelogenin family of extracellular matrix proteins. Amelogenins are involved in biomineralization during tooth enamel development. Mutations in a related gene on chromosome X cause X-linked amelogenesis imperfecta. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | AMELY |
| Reactivity | Human |
| Applications | WB |
| MW(Calculated) | 23kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human AMELY.AA range 17-57 |
| Specificity | This antibody detects endogenous levels of AMELY at Human |
| Gene Name | AMELY AMGL AMGY |
| Protein Name | AMELY |
| Other Name | |
| Species | Human |
| Gene ID | 266 |
| Uniprot | Q99218 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Secreted, extracellular space, extracellular matrix. |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | developmental stage:Transiently but abundantly expressed by ameloblasts during tooth development. Amelogenin is the predominant protein in developing dental enamel.,Function:Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel.,miscellaneous:This isoform is encoded on the Y chromosome.,similarity:Belongs to the amelogenin family., |
