SKU: WP13056 Categories: ,

MAGE-9 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP13056-100
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Product details

Background:

This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetMAGE9
ReactivityHuman
ApplicationsIHC, IF, ELISA
MW(Calculated)35kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioIHC 1:100-1:300; ELISA 1:40000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from MAGE-9 . at AA range: 1-80
SpecificityMAGE-9 Polyclonal Antibody detects endogenous levels of MAGE-9 protein.
Gene NameMAGEA9
Protein NameMelanoma-associated antigen 9
Other NameMAGEA9; / MAGE9; / MAGEA9A; / MAGEA9B; / Melanoma-associated antigen 9; / Cancer/testis antigen 1.9; / CT1.9; / MAGE-9 antigen
SpeciesHuman
Gene ID4108;728269
UniprotP43362
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Tissue ExpressionExpressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes and placenta.
Signaling_pathway
Research Areas
FunctionFunction:Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression.,similarity:Contains 1 MAGE domain.,tissue specificity:Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes and placenta.,
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