SKU: WP2436 Categories: ,

REL1 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP2436-100
Enter the quantity you would like, or drag the panel to find the quantity and price that best for you
Bulk QuoteAuthorize OEM & ODM

Product details

Background:

relaxin 1(RLN1) Homo sapiens Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In humans there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3, where RLN1 and RLN2 share high sequence homology. The protein encoded by this gene is synthesized as a single-chain polypeptide but the active form consists of an A chain and a B chain linked by disulfide bonds. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. [provided by RefSeq, Jan 2013],

Specifications

Size50μL/100μL
TargetREL1
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)20kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from part region of human protein
SpecificityREL1 Polyclonal Antibody detects endogenous levels of protein.
Gene NameRLN1
Protein NameProrelaxin H1 [Cleaved into: Relaxin B chain; Relaxin A chain]
Other Name
SpeciesHuman
Gene ID6013
UniprotP04808,
Species.1Mouse
Gene ID.1
Uniprot.1P47932,
Species.2Rat
Gene ID.2
Uniprot.2P01347
Cellular LocalizationSecreted.
Tissue ExpressionProstate. Not expressed in placenta, decidua or ovary.
Signaling_pathwayOrganismal Systems >> Endocrine system >> Relaxin signaling pathway
Research Areas>>Neuroactive ligand-receptor interaction; / >>Relaxin signaling pathway
FunctionFunction:Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix.,similarity:Belongs to the insulin family.,subunit:Heterodimer of a B chain and an A chain linked by two disulfide bonds.,tissue specificity:Prostate. Not expressed in placenta, decidua or ovary.,
Please login to post questions
Back to Top
Product has been added to your cart