Product details
Background:
The protein encoded by this gene regulates the development of red pulp macrophages, which are necessary for iron homeostasis and the recycling of red blood cells. [provided by RefSeq, Aug 2016],
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Spi-C Polyclonal Antibody
Ucallm_WP14556-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | Spi-C |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA, IHC |
| MW(Calculated) | |
| MW(Observed) | 29kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SPIC. AA range:131-180 |
| Specificity | Spi-C Polyclonal Antibody detects endogenous levels of Spi-C protein. |
| Gene Name | SPIC |
| Protein Name | Transcription factor Spi-C |
| Other Name | SPIC; / Transcription factor Spi-C |
| Species | Human |
| Gene ID | 121599 |
| Uniprot | Q8N5J4, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q6P3D7 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . |
| Tissue Expression | Preferentially detected in fetal and adult spleen, lymph nodes and at lower levels in bone marrow and fetal liver. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Probable transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer.,similarity:Belongs to the ETS family.,similarity:Contains 1 ETS DNA-binding domain.,subunit:Binds DNA as a monomer.,tissue specificity:Preferentially detected in fetal and adult spleen, lymph nodes and at lower levels in bone marrow and fetal liver., |
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