Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human SRI
Specificity
This antibody detects endogenous levels of SRI at Human, Mouse
Gene Name
SRI
Protein Name
Sorcin (22 kDa protein) (CP-22) (CP22) (V19)
Other Name
Species
Human
Gene ID
6717
Uniprot
P30626,
Species.1
Mouse
Gene ID.1
109552
Uniprot.1
Q6P069
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Cytoplasm. Sarcoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Relocates to the sarcoplasmic reticulum membrane in response to elevated calcium levels.
Tissue Expression
Detected in cardiac myocytes.
Signaling_pathway
Research Areas
Function
Calcium-binding protein that modulates excitation-contraction coupling in the heart. Contributes to calcium homeostasis in the heart sarcoplasmic reticulum. Modulates the activity of RYR2 calcium channels.