TCF25 is a member of the basic helix-loop-helix (bHLH) family of transcription factors that are important in embryonic development (Steen and Lindholm, 2008 [PubMed 18068114]).[supplied by OMIM, Sep 2008],
Specifications
Size
50μL/100μL
Target
TCF25
Reactivity
Human, Mouse
Applications
WB, ELISA
MW(Calculated)
MW(Observed)
74kD
Host Species
Rabbit
Isotype
IgG
Conjugate/Modification
Unmodified
Recommended Dilution Ratio
WB 1:500-2000; ELISA 1:5000-20000
Formulation
Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
TCF25 Polyclonal Antibody detects endogenous levels of protein.
Gene Name
TCF25 KIAA1049 NULP1 FKSG26
Protein Name
Transcription factor 25 (TCF-25) (Nuclear localized protein 1)
Other Name
Species
Human
Gene ID
22980
Uniprot
Q9BQ70,
Species.1
Mouse
Gene ID.1
Uniprot.1
Q8R3L2
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Nucleus . Some staining in the cytosol.
Tissue Expression
In the embryo, widely expressed with highest levels in brain. In the adult, highest expression is found in the heart.
Signaling_pathway
Research Areas
Function
Domain:The C-terminal region mediates transcriptional repression.,Function:May play a role in cell death control. Acts as a transcriptional repressor. Has been shown to repress transcription of SRF in vitro and so may play a role in heart development.,similarity:Belongs to the TCF25 family.,subcellular location:Some staining in the cytosol.,subunit:Interacts with XIAP.,tissue specificity:In the embryo, widely expressed with highest levels in brain. In the adult, highest expression is found in the heart.,