SKU: WP1847 Categories: ,

TCF25 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP1847-100
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Product details

Background:

TCF25 is a member of the basic helix-loop-helix (bHLH) family of transcription factors that are important in embryonic development (Steen and Lindholm, 2008 [PubMed 18068114]).[supplied by OMIM, Sep 2008],

Specifications

Size50μL/100μL
TargetTCF25
ReactivityHuman, Mouse
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)74kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from part region of human protein
SpecificityTCF25 Polyclonal Antibody detects endogenous levels of protein.
Gene NameTCF25 KIAA1049 NULP1 FKSG26
Protein NameTranscription factor 25 (TCF-25) (Nuclear localized protein 1)
Other Name
SpeciesHuman
Gene ID22980
UniprotQ9BQ70,
Species.1Mouse
Gene ID.1
Uniprot.1Q8R3L2
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationNucleus . Some staining in the cytosol.
Tissue ExpressionIn the embryo, widely expressed with highest levels in brain. In the adult, highest expression is found in the heart.
Signaling_pathway
Research Areas
FunctionDomain:The C-terminal region mediates transcriptional repression.,Function:May play a role in cell death control. Acts as a transcriptional repressor. Has been shown to repress transcription of SRF in vitro and so may play a role in heart development.,similarity:Belongs to the TCF25 family.,subcellular location:Some staining in the cytosol.,subunit:Interacts with XIAP.,tissue specificity:In the embryo, widely expressed with highest levels in brain. In the adult, highest expression is found in the heart.,
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