Product details
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TMOD1 rabbit pAb
Ucallm_WP6367-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | TMOD1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 39kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human TMOD1 |
| Specificity | This antibody detects endogenous levels of TMOD1 at Human, Mouse,Rat |
| Gene Name | TMOD1 D9S57E TMOD |
| Protein Name | Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod) |
| Other Name | |
| Species | Human |
| Gene ID | 7111 |
| Uniprot | P28289, |
| Species.1 | Mouse |
| Gene ID.1 | 21916 |
| Uniprot.1 | P49813, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | P70567 |
| Cellular Localization | Cytoplasm, cytoskeleton . In myofibrils with sarcomeric structure, localizes to the pointed end of actin thin filaments (PubMed:25250574). . |
| Tissue Expression | Highly expressed in the erythrocyte, heart and skeletal muscle. |
| Signaling_pathway | |
| Research Areas | |
| Function | Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus. |
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