SKU: WP6371 Categories: ,

TXNDC4 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP6371-100
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Product details

Background:

Specifications

TargetERP44
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)45kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Modification
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human TXNDC4
Sequence
SpecificityThis antibody detects endogenous levels of TXNDC4 at Human, Mouse
Gene NameERP44 KIAA0573 TXNDC4 UNQ532/PRO1075
Protein NameEndoplasmic reticulum resident protein 44 (ER protein 44) (ERp44) (Thioredoxin domain-containing protein 4)
Other Name
SpeciesHuman
Gene ID-123071
UniprotQ9BS26,
Species.1Mouse
Gene ID-276299
Uniprot.1Q9D1Q6
Species.2
Gene ID-3
Uniprot.2
Organism-4
Gene ID-4
SwissProt-4
Background
Cellular LocalizationEndoplasmic reticulum lumen .
Tissue Expression
Signaling_pathway
Research Areas
FunctionMediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1A and ERO1B in the endoplasmic reticulum.
RRID
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