Name: Eotaxin-3 Polyclonal Antibody
SKU: WP15234
Price: 268 USD
Availability: InStock

Eotaxin-3 Polyclonal Antibody

Ucallm_WP15234-50

Price range: $268.00 through $328.00

Size

100μl

50μl

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SKU: WP15234-100

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Product details

Background:

This gene is one of two Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 7. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for normal peripheral blood eosinophils and basophils. The product of this gene is one of three related chemokines that specifically activate chemokine receptor CCR3. This chemokine may contribute to the eosinophil accumulation in atopic diseases. [provided by RefSeq, Jul 2008],

Specifications

Size	50μL/100μL
Target	Eotaxin-3
Reactivity	Human
Applications	WB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)	12kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-1:2000; IHC: 1:100-300; ELISA 1:20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	The antiserum was produced against synthesized peptide derived from the Internal region of human CCL26. AA range:31-80
Specificity	Eotaxin-3 Polyclonal Antibody detects endogenous levels of Eotaxin-3 protein.
Gene Name	CCL26
Protein Name	C-C motif chemokine 26
Other Name	CCL26; / SCYA26; / C-C motif chemokine 26; / CC chemokine IMAC; / Eotaxin-3; / Macrophage inflammatory protein 4-alpha; / MIP-4-alpha; / Small-inducible cytokine A26; / Thymic stroma chemokine-1; / TSC-1
Species	Human
Gene ID	10344
Uniprot	Q9Y258
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	Secreted .
Tissue Expression	Ubiquitously expressed at low levels in various tissues including heart and ovary.
Signaling_pathway	Organismal Systems >> Immune system >> Chemokine signaling pathway;Environmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction;Environmental Information Processing >> Signaling molecules and interaction >> Viral protein interaction with cytokine and cytokine receptor
Research Areas	>>Cytokine-cytokine receptor interaction; / >>Viral protein interaction with cytokine and cytokine receptor; / >>Chemokine signaling pathway
Function	Function:Chemotactic for eosinophils and basophils. Binds to CCR3.,online information:CCL26 entry,similarity:Belongs to the intercrine beta (chemokine CC) family.,subunit:Monomer.,tissue specificity:Ubiquitously expressed at low levels in various tissues including heart and ovary.,