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GLDN rabbit pAb
Ucallm_WP16411-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | GLDN |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 61kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human GLDN AA range: 461-511 |
| Specificity | This antibody detects endogenous levels of GLDN at Human/Mouse/Rat |
| Gene Name | GLDN COLM UNQ9339/PRO34011 |
| Protein Name | GLDN |
| Other Name | |
| Species | Human |
| Gene ID | 342035 |
| Uniprot | Q6ZMI3, |
| Species.1 | Mouse |
| Gene ID.1 | 235379 |
| Uniprot.1 | Q8BMF8, |
| Species.2 | Rat |
| Gene ID.2 | 315675 |
| Uniprot.2 | Q80WL1 |
| Cellular Localization | Cell membrane; Single-pass type II membrane protein . Cell projection, axon . Detected at the nodes of Ranvier. Detected at immature heminodes. .; [Gliomedin shedded ectodomain]: Secreted . Secreted, extracellular space, extracellular matrix . Proteolytic processing gives rise to a soluble extracellular domain that is secreted. The gliomedin shedded ectodomain localizes to the nodes of Ranvier. . |
| Tissue Expression | Specifically expressed in spinal cord, brain, placenta and sciatic nerve. More abundant in peripheral than central nervous system. |
| Signaling_pathway | |
| Research Areas | |
| Function | Domain:The olfactomedin-like domain mediates NFASC/neurofascin and NRCAM binding.,Function:Plays a role in the formation of the nodes of Ranvier along myelinated axons. Probable NRCAM and NFASC/neurofascin ligand which may provide a glial positional clue required for the proper molecular assembly of the nodes of Ranvier.,similarity:Contains 1 olfactomedin-like domain.,similarity:Contains 2 collagen-like domains.,subcellular location:Localizes to the nodes of Ranvier.,subunit:Interacts with NFASC/neurofascin and NRCAM.,tissue specificity:Specifically expressed in spinal cord, brain, placenta and sciatic nerve. More abundant in peripheral than central nervous system., |
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