Product details
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MEMO1 rabbit pAb
Ucallm_WP8297-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | MEMO1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 33kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human MEMO1 |
| Specificity | This antibody detects endogenous levels of MEMO1 at Human, Mouse,Rat |
| Gene Name | MEMO1 C2orf4 MEMO NS5ATP7 CGI-27 |
| Protein Name | Protein MEMO1 (C21orf19-like protein) (Hepatitis C virus NS5A-transactivated protein 7) (HCV NS5A-transactivated protein 7) (Mediator of ErbB2-driven cell motility 1) (Mediator of cell motility 1) (Memo-1) |
| Other Name | |
| Species | Human |
| Gene ID | 51072 |
| Uniprot | Q9Y316, |
| Species.1 | Mouse |
| Gene ID.1 | 76890 |
| Uniprot.1 | Q91VH6, |
| Species.2 | Rat |
| Gene ID.2 | 298787 |
| Uniprot.2 | Q4QQR9 |
| Cellular Localization | |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Is required for breast carcinoma cell migration. |
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