Name: TRMT61B rabbit pAb
SKU: WP6872
Price: 268 USD
Availability: InStock

TRMT61B rabbit pAb

Ucallm_WP6872-50

Price range: $268.00 through $328.00

Size

100μl

50μl

Clear

SKU: WP6872-100

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Product details

Background:

Specifications

Size	50μL/100μL
Target	TRMT61B
Reactivity	Human
Applications	WB
MW(Calculated)	52kD
MW(Observed)
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-2000
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	Synthesized peptide derived from human TRMT61B
Specificity	This antibody detects endogenous levels of TRMT61B at Human
Gene Name	TRMT61B
Protein Name	Potential tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61B (EC 2.1.1.220)
Other Name
Species	Human
Gene ID	55006
Uniprot	Q9BVS5
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	Mitochondrion .
Tissue Expression
Signaling_pathway
Research Areas
Function	Methyltransferase that catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in various tRNAs in mitochondrion, including tRNA(Leu) (deciphering codons UUA or UUG), tRNA(Lys) and tRNA(Ser) (deciphering codons UCA, UCU, UCG or UCC) . Catalyzes the formation of 1-methyladenosine at position 947 of mitochondrial 16S ribosomal RNA and this modification is most likely important for mitoribosomal structure and function . In addition to tRNA N(1)-methyltransferase activity, also acts as a mRNA N(1)-methyltransferase by mediating methylation of adenosine residues at the N(1) position of MT-ND5 mRNA, leading to interfere with mitochondrial translation .