Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human TXNDC3
Specificity
This antibody detects endogenous levels of TXNDC3 at Human, Mouse,Rat
Gene Name
NME8 SPTRX2 TXNDC3
Protein Name
Thioredoxin domain-containing protein 3 (NM23-H8) (NME/NM23 family member 8) (Spermatid-specific thioredoxin-2) (Sptrx-2)
Other Name
Species
Human
Gene ID
51314
Uniprot
Q8N427,
Species.1
Mouse
Gene ID.1
73412
Uniprot.1
Q715T0,
Species.2
Rat
Gene ID.2
Uniprot.2
Q715S9
Cellular Localization
Cytoplasm .
Tissue Expression
Testis-specific. Expressed only in primary spermatocytes and round spermatids.
Signaling_pathway
Research Areas
Function
Probably required during the final stages of sperm tail maturation in the testis and/or epididymis, where extensive disulfide bonding of fibrous sheath (FS) proteins occurs. May be involved in the reduction of disulfide bonds within the sperm FS components. In vitro, it has neither NDP kinase nor reducing activity on disulfide bonds.