Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human EPSTI1
Specificity
This antibody detects endogenous levels of EPSTI1 at Human, Mouse,Rat
Gene Name
EPSTI1
Protein Name
Epithelial-stromal interaction protein 1
Other Name
Species
Human
Gene ID
94240
Uniprot
Q96J88,
Species.1
Mouse
Gene ID.1
108670
Uniprot.1
Q8VDI1,
Species.2
Rat
Gene ID.2
498547
Uniprot.2
Q5BK43
Cellular Localization
Tissue Expression
Highly expressed in placenta, small intestine, spleen, kidney, thymus, liver, salivary gland and testes. Weakly expressed in breast, skeletal muscle and colon. Highly expressed in breast cancer upon interaction between tumor cells and stromal cells in vitro. Expressed in blood mononuclear cells from patients with systemic lupus erythematosus (SLE).
Signaling_pathway
Research Areas
Function
Plays a role in M1 macrophage polarization and is required for the proper regulation of gene expression during M1 versus M2 macrophage differentiation (By similarity). Might play a role in RELA/p65 and STAT1 phosphorylation and nuclear localization upon activation of macrophages (By similarity).