SKU: WP6838 Categories: ,

EPSTI1 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP6838-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetEPSTI1
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)35kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human EPSTI1
SpecificityThis antibody detects endogenous levels of EPSTI1 at Human, Mouse,Rat
Gene NameEPSTI1
Protein NameEpithelial-stromal interaction protein 1
Other Name
SpeciesHuman
Gene ID94240
UniprotQ96J88,
Species.1Mouse
Gene ID.1108670
Uniprot.1Q8VDI1,
Species.2Rat
Gene ID.2498547
Uniprot.2Q5BK43
Cellular Localization
Tissue ExpressionHighly expressed in placenta, small intestine, spleen, kidney, thymus, liver, salivary gland and testes. Weakly expressed in breast, skeletal muscle and colon. Highly expressed in breast cancer upon interaction between tumor cells and stromal cells in vitro. Expressed in blood mononuclear cells from patients with systemic lupus erythematosus (SLE).
Signaling_pathway
Research Areas
FunctionPlays a role in M1 macrophage polarization and is required for the proper regulation of gene expression during M1 versus M2 macrophage differentiation (By similarity). Might play a role in RELA/p65 and STAT1 phosphorylation and nuclear localization upon activation of macrophages (By similarity).
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