Name: TRIM6 rabbit pAb
SKU: WP6808
Price: 268 USD
Availability: InStock

TRIM6 rabbit pAb

Ucallm_WP6808-50

Price range: $268.00 through $328.00

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SKU: WP6808-100

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Product details

Background:

Specifications

Size	50μL/100μL
Target	TRIM6
Reactivity	Human, Mouse
Applications	WB
MW(Calculated)	54kD
MW(Observed)
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-2000
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	Synthesized peptide derived from human TRIM6
Specificity	This antibody detects endogenous levels of TRIM6 at Human, Mouse
Gene Name	TRIM6 RNF89
Protein Name	Tripartite motif-containing protein 6 (RING finger protein 89)
Other Name
Species	Human
Gene ID	117854
Uniprot	Q9C030,
Species.1	Mouse
Gene ID.1	94088
Uniprot.1	Q8BGE7
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	Cytoplasm .
Tissue Expression
Signaling_pathway
Research Areas
Function	E3 ubiquitin ligase that plays a crucial role in the activation of the IKBKE-dependent branch of the type I interferon signaling pathway . In concert with the ubiquitin-conjugating E2 enzyme UBE2K, synthesizes unanchored 'Lys-48'-linked polyubiquitin chains that promote the oligomerization and autophosphorylation of IKBKE leading to stimulation of an antiviral response . Ubiquitinates also MYC and inhibits its transcription activation activity, maintaining the pluripotency of embryonic stem cells (By similarity).

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